Our Services
Replication study (RCA)
RCA (Replication Combing Assay) is an innovative approach that gives you insight into replication fork dynamics. Mainly for oncology and drug discovery.
Structural Variations (QCA)
QCA (Quality Control Assay) is a powerful solution for the control and optimization of genome editing. Mainly for gene therapy and biomanufacturing.
Telomere study (TeloSizer®)
TeloSizer® is the novel assay based on molecular combing and physical telomere analysis. Mainly for cancer and ageing studies.
Services delivery, provision, offer(s)
Interested in outsourcing some steps of your experiment to accelerate timelines and maximize efficiency ? Our service team is ready to process your samples for different applications.
Replication study
(Replication Combing Assay – RCA)
Want to assess drug efficacy or replication mechanisms ? RCA (Replication Combing Assay) is an innovative approach that gives you insight into replication fork dynamics.
Following your experimental design, you can precisely measure tracks length from multiple single DNA molecules and evaluate several replication parameters :
• Calculate fork speed,
• Quantify origin firing / inter-origin distances,
• Fork stalling and restart,
• Fork protection,
• Fork progression.
If you want to know more about our RCA service, contact our sales team.
Structural Variations (QCA)
QCA (Quality Control Assay) is a powerful solution for the control and optimization of genome editing. Mainly for gene therapy and biomanufacturing.
Want to validate cell lines or animal models ? QCA (Quality Control Assay) is a powerful solution, based on molecular combing technology, for the control and optimization of genome editing.
After the design of FiberProbes® specific to your region of interest, you can assess quantitatively and qualitatively all kind of structural variations on multiple single DNA molecules :
• Confirm wanted editing events,
• Detect unexpected events >2kb (such as deletions, insertions, inversions),
• Quantify off-target/on-target insertion,
• Determine copy number variations.
Resolution 2kb – 2Mb
Rare events visualization down to XX% frequency
You can also use it for gene therapy. We can look at any locus.
If you want to know more about our QCA service, contact our sales team.
Telomere study TeloSizer®
TeloSizer® assay is the novel tool for measurements of physical telomere length that can be applied to various model organisms.
After telomere probes hybridization, you will be able to determine :
• mean telomere length,
• distribution of individual telomere length in a cell population.
TeloSizer® enables the detection of telomeric sequences, distinguishing between TTS (True Telomeric Sequences) and ITS (Interstitial Telomeric Sequences).
Resolution 2 kb to > 300 kb
If you want to know more about our TeloSizer® service delivery, contact our sales team.
Services delivery / provision / offer(s)
EasyComb Service
You want to entrust your project to molecular combing experts ? From DNA extraction to image acquisition, we take care of everything.
Once the samples processed, you can access your results using our web application : analyze your signals with simplicity and accuracy.
EasyComb Plus Service
If you are not willing to do the analysis yourself, opt for an EasyComb Plus Service: we do it for you! The report analysis will be directly released to you.
EasyScan Service
You want to avoid manual image acquisition and get all the signals in one picture.
Send us your coverslips with combed and labelled DNA and our automated scanner will scan the whole surface.
The service also allows you to benefit from our web application to directly visualize, categorize and measure signals of interest with accuracy.
