1. Structural variability of the herpes simplex virus 1 genome in vitro and in vivo.
    Mahiet C, Ergani A, Huot N, Alende N, Azough A, Salvaire F, Bensimon A, Conseiller E, Wain-Hobson S, Labetoulle M, Barradeau S.
    J Virol. 2012 Aug;86(16):8592-601.
  2. A diagnostic genetic test for the physical mapping of germline rearrangements in the susceptibility breast cancer genes BRCA1 and BRCA2.
    Cheeseman K, Rouleau E, Vannier A, Thomas A, Briaux A, Lefol C, Walrafen P, Bensimon A, Lidereau R, Conseiller E, Ceppi M.
    Hum Mutat. 2012 Jun. 2012 Apr 4;33(6):998-1009.
  3. Molecular combing reveals allelic combinations in facioscapulohumeral dystrophy.
    Nguyen K, Walrafen P, Bernard R, Attarian S, Chaix C, Vovan C, Renard E, Dufrane N, Pouget J, Vannier A, Bensimon A, Lévy N.
    Ann Neurol. 2011 Oct 25;70(4):627-33.
  4. Failure of origin activation in response to fork stalling leads to chromosomal instability at fragile sites.
    Ozeri-Galai E, Lebofsky R, Rahat A, Bester AC, Bensimon A, Kerem B.
    Mol Cell. 2011 Jul 8;43(1):122-31.
  5. Microtriplication of 11q24.1: a highly recognisable phenotype with short stature, distinctive facial features, keratoconus, overweight, and intellectual disability .
    Beneteau C, Landais E, Doco-Fenzy M, Gavazzi C, Philippe C, Béri-Dexheimer M, Bonnet C, Vigneron J, Walrafen P, Motte J, Leheup B, Jonveaux P .
    J Med Genet. 2011 May;.
  6. Nucleotide deficiency promotes genomic instability in early stages of cancer development.
    Bester AC, Roniger M, Oren YS, Im MM, Sarni D, Chaoat M, Bensimon A, Zamir G, Shewach DS, Kerem B.
    Cell. 2011 Apr 29;145(3):435-46.
  7. The Dynamic Replicon: adapting to a changing cellular environment.
    Herrick J.
    Bioessays. 2010 Feb;32(2):153-64. Review.
  8. Combing genomic DNA for structural and functional studies.
    Schurra C, Bensimon A.
    Methods Mol Biol. 2009;464:71-90.
  9. The Hsk1(Cdc7) Replication Kinase Regulates Origin Efficiency.
    Patel PK, Kommajosyula N, Rosebrock A, Bensimon A, Leatherwood J, Bechhoefer J, Rhind N.
    Mol Biol Cell. 2008 Dec;19(12):5550-5558.
  10. Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.
    Herrick J, Bensimon A.
    Chromosoma. 2008 Jun;117(3):243-60.
  11. A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.
    Montagnoli A, Valsasina B, Croci V, Menichincheri M, Rainoldi S, Marchesi V, Tibolla M, Tenca P, Brotherton D, Albanese C, Patton V, Alzani R, Ciavolella A, Sola F, Molinari A, Volpi D, Avanzi N, Fiorentini F, Cattoni M, Healy S, Ballinari D, Pesenti E, Isacchi A, Moll J, Bensimon A, Vanotti E, Santocanale C.
    Nat Chem Biol. 2008 Jun;4(6):357-65.
  12. Introduction to Molecular Combing: Genomics, DNA replication and Cancer.
    Herrick J, Bensimon A.
    Methods in Molecular Biology, DNA replication. 2008;Vol 521. Humana Press. Sonya Vengrova and Jacob Z. Dogaard (editors).
  13. Milestones and Perspectives in Molecular Combing.
    Herrick J, Bensimon A.
    2008;(manuscript in preparation).
  14. Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells.
    Conti C, Saccà B, Herrick J, Lalou C, Pommier Y, Bensimon A.
    Mol Biol Cell. 2007 Aug;18(8):3059-67.
  15. Unscheduled DNA replication origin activation at inserted HPV 18 sequences in a HPV-18/MYC amplicon.
    Conti C, Herrick J, Bensimon A.
    Genes Chromosomes Cancer. 2007 Aug;46(8):724-34.
  16. Endogenous gamma-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase deficient cells is related to DNA replication arrested forks.
    Rao VA, Conti C, Guirouilh-Barbat J, Nakamura A, Miao ZH, Davies SL, Saccá B, Hickson ID, Bensimon A, Pommier Y.
    Mol Cancer Res. 2007 Jul;5(7):713-24.
  17. Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint.
    Pillaire MJ, Betous R, Conti C, Czaplicki J, Pasero P, Bensimon A, Cazaux C, Hoffmann JS.
    Cell Cycle. 2007 Feb;6(4):471-7.
  18. DNA replication origin interference increases the spacing between initiation events in human cells.
    Lebofsky R, Heilig R, Sonnleitner M, Weissenbach J, Bensimon A.
    Mol Biol Cell. 2006 Dec;17(12):5337-45.
  19. DNA replication origin interference increases the spacing between initiation events in human cells .
    Lebofsky R, Heilig R, Sonnleitner M, Weissenbach J, Bensimon A.
    Mol Biol Cell. 2006 Dec;17(12):5337-45.
  20. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
    Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre' M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, d'Adda di Fagagna F.
    Nature. 2006 Nov;444(7119):638-42.
  21. DNA replication origins fire stochastically in fission yeast.
    Patel PK, Arcangioli B, Baker SP, Bensimon A, Rhind N.
    Mol Biol Cell. 2006 Jan;17(1):308-16.
  22. Methods to study replication fork collapse in budding yeast.
    Liberi G, Cotta-Ramusino C, Lopes M, Sogo J, Conti C, Bensimon A, Foiani M.
    Methods Enzymol. 2006 Jan;409:442-62.
  23. Human ribosomal RNA gene arrays display a broad range of palindromic structures.
    Caburet S, Conti C, Schurra C, Lebofsky R, Edelstein SJ, Bensimon A.
    Genome Res. 2005 Aug;15(8):1079-85.
  24. DNA replication origin plasticity and perturbed fork progression in human inverted repeats.
    Lebofsky R, Bensimon A.
    Mol Cell Biol. 2005 Aug;25(15):6789-97.
  25. Genomic organization of amplified MYC genes suggests distinct mechanisms of amplification in tumorigenesis.
    Herrick J, Conti C, Teissier S, Thierry F, Couturier J, Sastre-Garau X, Favre M, Orth G, Bensimon A.
    Cancer Res. 2005 Feb;65(4):1174-9.
  26. Persistence length of chromatin determines origin spacing in Xenopus early-embryo DNA replication: quantitative comparisons between theory and experiment.
    Jun S, Herrick J, Bensimon A, Bechhoefer J.
    Cell Cycle. 2004 Feb;3(2):223-9.
  27. Persistence length of chromatin determines origin spacing in Xenopus early-embryo DNA replication: quantitative comparisons between theory and experiment.
    Jun S, Herrick J, Bensimon A, Bechhoefer J.
    Cell Cycle. 2004 Feb;3(2):223-9.
  28. Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing.
    Anglana M, Apiou F, Bensimon A & Debatisse M.
    Cell. 2003 Aug;114, 385-394.
  29. Characterisation of a 161 kb deletion extending from the NBR1 to the BRCA1 genes in a French breast-ovarian cancer family.
    Gad S, Bieche I, Barrois M, Casilli F, Pages-Berhouet S, Dehainault C, Gauthier-Villars M, Bensimon A, Aurias A, Lidereau R, Bressac-de Paillerets B, Tosi M, Mazoyer S, Stoppa-Lyonnet D.
    Hum Mutat. 2003 Jun;21(6):654.
  30. Single DNA molecule analysis: applications of molecular combing.
    Lebofsky R, Bensimon A.
    Brief Funct Genomic Proteomic. 2003 Jan;1(4):385-96.
  31. Bar code screening on combed DNA for large rearrangements of the BRCA1 and BRCA2 genes in French breast cancer families.
    Gad S, Klinger M, Caux-Moncoutier V, Pages-Berhouet S, Gauthier-Villars M, Coupier I, Bensimon A, Aurias A & Stoppa-Lyonnet D.
    J Med Genet. 2002 Nov;39(11):817-21.
  32. Significant contribution of large BRCA1 gene rearrangements in 120 French breast and ovarian cancer families.
    Gad S, Caux-Moncoutier V, Pagès-Berhouet S, Gauthier-Villars M, Coupier I, Pujol P, Frénay M, Gilbert B, Maugard C, Bignon YJ, Chevrier A, Rossi A, Fricker JP, Nguyen TD, Demange L, Aurias A, Bensimon A, Stoppa-Lyonnet D.
    Oncogene. 2002 Oct;21(44):6841-7.
  33. A combinatorial approach for fast, high-resolution mapping.
    Conti C & Bensimon A.
    Genomics. 2002 Aug;80, 135-137.
  34. Combing the genome for genomic instability.
    Caburet S, Conti C & Bensimon A.
    Trends Biotechnol. 2002 Aug;20, 344-350.
  35. Kinetic model of DNA replication in eukaryotic organisms.
    Herrick J, Jun S, Bechhoefer J, Bensimon A.
    J Mol Biol. 2002 Jul;320(4):741-50.
  36. Targeting the molecular mechanism of DNA replication.
    Conti C, Caburet S & Bensimon A.
    Drug Discov Today. 2001 Aug;6, 786-792.
  37. Identification of a large rearrangement of the BRCA1 gene using colour bar code on combed DNA in an American breast/ovarian cancer family previously studied by direct sequencing.
    Gad, S., Scheuner, M.T., Pages-Berhouet, S., Caux-Moncoutier, V., Bensimon, A., Aurias, A., Pinto, M. & Stoppa-Lyonnet, D.
    J Med Genet. 2001 Jun;38(6):388-92.
  38. Color bar coding the BRCA1 gene on combed DNA: a useful strategy for detecting large gene rearrangements.
    Gad S, Aurias A, Puget N, Mairal A, Schurra C, Montagna M, Pages S, Caux V, Mazoyer S, Bensimon A & Stoppa-Lyonnet D.
    Genes Chromosomes Cancer. 2001 May;31(1):75-84.
  39. Replication fork density increases during DNA synthesis in X. laevis egg extracts.
    Herrick J, Stanislawski P, Hyrien O, Bensimon A.
    J Mol Biol. 2000 Jul;300(5):1133-42.
  40. Quantifying single gene copy number by measuring fluorescent probe lengths on combed genomic DNA.
    Herrick J, Michalet X, Conti C, Schurra C, Bensimon A.
    Proc Natl Acad Sci U S A. 2000 Jan;97(1):222-7.
  41. Single molecule analysis of DNA replication.
    Herrick J, Bensimon A.
    Biochimie. 1999 Aug;81(8-9):859-71.
  42. Imaging of single DNA molecule: applications to high-resolution genomic studies.
    Herrick J, Bensimon A.
    Chromosome Res. 1999 Jan;7(6):409-23.
  43. Dynamic molecular combing: stretching the whole human genome for high- resolution studies.
    Michalet X, Ekong R, Fougerousse F, Rousseaux S, Schurra C, Hornigold N, van Slegtenhorst M, Wolfe J, Povey S, Beckmann JS & Bensimon A.
    Science. 1997 Jul;277, 1518-1523.
  44. Alignment and sensitive detection of DNA by a moving interface.
    Bensimon A, Simon A, Chiffaudel A, Croquette V, Heslot F & Bensimon D.
    Science. 1994 Sep;265, 2096-2098.
Genomic Vision