Tailor made solutions for quality control of genome engineering
The Molecular Combing technology provides a powerful quality control tool for the optimization of gene editing technologies aimed at therapy and also to validate edited cell lines and animal models.
We offer our combing services to allow our customers to
Validate the planned gene editing events
Detect incorrect events larger than 1kb – incorrect deletions, insertions or inversions
Quantify Off-target / On-target Ratio
Please contact us for more information at
A quantitative and qualitative approach for Genome Engineering Quality Control
> Unbiased assessment of editing events thanks to the direct visualization on single DNA molecules
> Any error larger than 1kb can be detected in the target locus
> Detection of rare events
> Multiplexing up to 5 loci
> The technology also allows the studies of DNA replication, Damage and Repair in a separate assay
A quantitative and qualitative approach for Genome Engineering Quality Control
> Unbiased assessment of editing events thanks to the direct visualization on single DNA molecules
> Any error larger than 1kb can be detected in the target locus
> Detection of rare events
> Multiplexing up to 5 loci
> The technology also allows the studies of DNA replication, Damage and Repair in a separate assay