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Molecular Combing is an accurate and powerful technology for studying the kinetics of DNA replication.

Alterations in DNA replication represent a major source of genomic instability in precancerous lesions and play a central role in the development of cancer (carcinogenesis). The recent development of single-molecule approaches opens new approaches to understand these phenomena.

We have developed the Replication Combing Assay to monitor the kinetics of DNA replication. This experimental assay provides an unrivalled capability in the analysis of DNA replication during normal or abnormal cell division. The Replication Combing Assay can:

• Identify and locate individual replication origins
• Study the kinetics of the DNA replication

Our objective is to provide Molecular Combing technology for fundamental research on DNA (cytogenetics and replication) and for applications in cancer research.

Genomic Vision is committed to helping research laboratories implement Molecular Combing by providing a set of tools, installation and ongoing technical and application support.

Genomic Vision operates under a specific agreement, which includes discounts on products and assistance with implementing Molecular Combing in the laboratory.

Download our DNA Replication factsheet to find out more.