Genomic Vision is a publicly-traded company on the Euronext regulated market in Paris
MOLECULAR COMBING FEATURED IN AN ORAL PRESENTATION ON CRISPR/Cas9 GENE EDITING AT THE 3rd CSHL MEETING IN NEW YORK
- The results presented demonstrate the capacity of molecular combing to characterize rearrangements formed as a result of CRISPR/Cas9-induced breaks and improve biosafety assessment of gene editing.
Bagneux (France), July 27, 2017 – Genomic Vision (FR0011799907 – GV), a company specialized in the development of diagnostic solutions for early cancer detection, genetic diseases and tools for life sciences research, today announced that the result of its collaboration with one of the leading genome editing companies has been presented during an oral presentation* at the 3rd Cold Spring Harbor Laboratory Meeting (CSHL) on Genome Engineering, held from July 21 to 23, 2017 in Cold Spring Harbor (NY).
In this collaboration, molecular combing was used to characterize the type and the frequency of DNA rearrangements formed as a result of CRISPR/Cas9-mediated gene editing on two disease loci. The results obtained with molecular combing complemented those provided by other approaches and contributed to a more comprehensive safety evaluation of the editing protocols.
Dr Lucia Cinque, Director of Product Innovation at Genomic Vision and co-author of the presentation, says: “The results of this study further reinforce our belief in the value of molecular combing for the development of safe genome editing applications. This is particularly important for therapeutic use, where quantification of rearrangements coupled with a thorough characterization of the ensuing cellular response is critical. This fruitful collaboration has not only shown the potential of molecular combing to leading experts in the field; it has also enabled Genomic Vision to promptly initiate key product improvements in order to facilitate a more wide-spread adoption of its technology as one of the essential tools for the quality and safety control of advanced genome editors.”
* Presentation Title: “Characterization of genomic rearrangements in response to CRISPR/Cas9-induced double strand breaks”(https://meetings.cshl.edu/abstracts.aspx?meet=CRISPR&year=17)
ABOUT GENOMIC VISION
GENOMIC VISION is a company specialized in the development of diagnostic solutions for the early detection of cancers and serious genetic diseases and tools for life sciences research. Through the DNA Molecular Combing, a strong proprietary technology allowing the identification of genetic abnormalities, GENOMIC VISION supports the R&D productivity of pharmaceutical companies, leaders in the diagnostic industry and research labs.
The Company develops a strong portfolio of diagnostic tests (breast and colorectal cancers, myopathies) and analysis tools (DNA replication, biomarkers discovery, gene editing quality control). Based in Bagneux, near Paris, the Company employs approximately 60 people. GENOMIC VISION is a public company listed on compartment C of Euronext’s regulated market in Paris (Euronext: GV – ISIN: FR0011799907). For further information, please visit www.genomicvision.com
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